Our vet recommended using the Feliway wipes for our 5 hour car ride to move to Atlanta. Between traffic, weather, and a whole slew of unfortunate events, our excursion really lasted closer to 10 hours in the car. No nausea, no hair loss, no howling...all I have is a happy relaxed kitty. We will not travel without Feliway again, and I will recommend them to anyone who has a poor traveler. Thank you!